RNA Details
Disease Name
atrial fibrillation
Tissue
heart
RNA Symbol
mir-29b-1
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
PCR; immunofluorescence etc.
Target
COL1A1;COL3A1;FBN
Pathway
NA
PubMed ID
Title
MicroRNA29 A Mechanistic Contributor and Potential Biomarker in Atrial Fibrillation
Year
2013
Function
"miR-29b can adjust the extracellular matrix col1a1, col3a1, and the expression of FBN, knockdown of miR-29b in mice significantly increased atrial COL1A1 mrna expression and cardiac tissue collagen content."